I'd vote for Janeane Garofalo. She and Sandra Bernhard will be appearing as lesbian lover biker chicks in an upcoming Sopranos episode - it's a series on HBO, or maybe it's Showtime.
I also heard Garofalo, an admitted feminist and Hillary Clinton fan, appeared opposite Ann Coulter on the TV show Politically Incorrect ... and gave her a licking. My dream Politically Incorrect show would include Garofalo, Christopher Hitchens, Jedediah Purdy and Max Sawicky. Or, substitute Sandra Bernahard for either Hitchens or Max.