Kills brain cells by depriving them of oxygen. Long-term exposure to high concentrations of nitrous oxide may cause megaloblastic bone-marrow depression and neurological symptoms. N2O also affects white blood cell production and function. Many anaesthesiologists believe that the potential dangers of N2O are so great that it should no longer be used at all for routine clinical anaesthesia. N2O induces opioid peptide release in the periaqueductal gray area of the midbrain. Better to just use opium.
John Thornton