The way I look at it, not only Muslim but also GLBT, feminist, and other predominantly secular activists have to change. The former have to change their ideas about families, gender roles, sexuality outside marriage, etc., for instance, and the latter have to change their view of Islam and Muslims (e.g., the views that Islam is a religion alien to Europe in particular and the West in general, that Muslim women, unlike women of other faiths, cannot but be victims unless they renounce their faith, etc. -- the views that some hold explicitly and many others subscribe to implicitly). So, quid pro quo, indeed.
In general, though, we won't find out the outcome of collaboration unless we begin it, and even if little of substance, in terms of political results, comes out of it in the short term, opportunities for debates and exchanges among secular and religious leftists are to be welcomed for their own sake.
On YouTube, DailyMotion, and other sites, numerous videos* of Tariq Ramadan, lecturing, debating, offering a prayer, etc. are available. I've watched some of them in full, and looked at what the others are about. It seems to me that, in the mainstream media, Ramadan is most often asked to debate white male European intellectuals who are conservative, Islamophobic, and anti-immigrant. Ramadan is very good at challenging them, and no doubt many Muslim immigrant youth are delighted by the sight of one of their own not only holding his own ground and effectively defending his constituency but also demonstrating to all fair observers that he is smarter, more cosmopolitan, and indeed perhaps more European in a good sense than any of his right-wing detractors. On the other hand, though, debates from which Ramadan, as well as his interlocutors and audiences, would most benefit would be not those with right-wingers but those with left-wingers, who agree with him on many points but disagree with him on some points. In the future, I hope there will be more of the latter.
Lastly, a note of caution. As you will see once you watch any of the Ramadan videos, he is a very polished public intellectual, but more in a way that Edward Said was or Cornel West is, rather than in a way that Malcolm X for instance was. That has something to do with his class backgrounds and education. It may be the case that some Muslim youth of the West, as well as many Muslim youth outside the West, are too oppressed and therefore too angry to listen to this very accomplished and sophisticated man with his message of republican citizenship, civil resistance, etc.
* Here are some of those videos:
Tariq Ramadan on Being European Muslims: <http://www.youtube.com/watch?v=3Qu-HBAOYl4> <http://www.youtube.com/watch?v=jRuHZhVh97Q> <http://www.youtube.com/watch?v=vARZkL-rxWc>
Tariq Ramadan sur OummaTV : « Réflexions sur notre identité culturelle, nos valeurs universelles et une résistance citoyenne pour une justice globale » <http://oumma.com/spip.php?article691>
Tariq Ramadan: <http://www.youtube.com/watch?v=TxQZLi94GBE> <http://www.youtube.com/watch?v=H-DrJtRykkc>
Tariq Ramadan, "Qui était véritablement le Prophète Muhammad ?" OummaTV: <http://oumma.com/spip.php?article2246>
"Face-à-face Tariq Ramadan et Philippe de Villiers," _Ripostes_, France 5: <http://www.dailymotion.com/video/x13346_ramadan-vs-de-villiers> <http://www.youtube.com/watch?v=3wz4t4mBWyY> <http://www.youtube.com/watch?v=2TlWJj6qim4>
Tariq Ramadan's Du'a for Palestine: <http://www.youtube.com/watch?v=onuEStqTk20>
Many others at <http://www.dailymotion.com/visited/search/tariq+ramadan/1>, etc. -- Yoshie <http://montages.blogspot.com/> <http://mrzine.org> <http://monthlyreview.org/>