Public Citizen's Health Research Group, which does a great service with their Worst Pills/Best Pills book and website, promotes a 5-year rule--don't take any medicine that hasn't been on the market for at least 5 years, since many drugs are withdrawn because of adverse effects in the first 5 years or found to have unforeseen side effects and interactions which the FDA may eventually force them to make public. For example, two friends of mine were recently put on a new birth control pill, Yasmin, which has no advantage over the dozens of other birth control pills on the market but did earn a "Do Not Take" designation from Public Citizen due to alarming cases of blood clots among women, some of whom had been taking it only a few weeks. Another example of that innovation we're always hearing capitalism is so good for.
Jenny Brown